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PREVNAR® 13 (pneumococcal 13-valent conjugate vaccine - diphtheria CRM197 protein) Nonclinical Toxicology


13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility

Prevnar 13 has not been evaluated for the potential to cause carcinogenicity, genotoxicity, or impairment of male fertility. In a study in rabbits, no vaccine-related effects were found regarding reproductive performance including female fertility [see Use in Specific Populations (8.1)].

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